{"_id":"MONDO:0019466","_version":1,"ctd":{"chemical_related_to_disease":{"cas_registry_number":"446-86-6","chemical_name":"Azathioprine","direct_evidence":"marker/mechanism","mesh_chemical_id":"D001379","pubmed":"19274043","source":"CTD"},"mesh":"D008230"},"disease_ontology":{"_license":"https://github.com/DiseaseOntology/HumanDiseaseOntology/blob/master/DO_LICENSE.txt","ancestors":["DOID:612","DOID:0060704","DOID:4","DOID:7","DOID:2914"],"children":["DOID:0081308","DOID:0081309","DOID:0081310"],"def":"\"A lymphoproliferative syndrome that is characterized by overproduction (proliferation) of white blood cells called lymphocytes. The abnormal cells infiltrate and accumulate (form lesions or nodules) within tissues. The lesions or nodules damage or destroy the blood vessels within these tissues.\" [url:https\\://rarediseases.org/rare-diseases/lymphomatoid-granulomatosis/]","descendants":["DOID:0081308","DOID:0081310","DOID:0081309"],"doid":"DOID:0081307","name":"lymphomatoid granulomatosis","parents":["DOID:0060704"],"synonyms":{},"xrefs":{"icd10":"C83.8","icdo":"9766/1","mesh":"D008230","ncit":"C7930","snomedct_us_2025_09_01":"60337005","umls_cui":"C0024307"}},"mondo":{"ancestors":["MONDO:0004949","MONDO:0015759","MONDO:0000001","MONDO:0045024","MONDO:0017343","MONDO:0005570","MONDO:0021669","MONDO:0017341","MONDO:0002334","MONDO:0005157","MONDO:0004805","MONDO:7770010","MONDO:0044881","MONDO:0017342","MONDO:7770008","MONDO:0005062","MONDO:0017595","MONDO:0005070","MONDO:7770006","MONDO:0005046","MONDO:0023370","MONDO:0700096","MONDO:0018905","MONDO:0004095","MONDO:0015757","MONDO:0021674","MONDO:0018908"],"children":["MONDO:0859747","MONDO:0859748","MONDO:0859749"],"definition":"A very rare Epstein-Barr virus (EBV)-driven lymphoproliferative disease most commonly occurring in adults (in the fourth to sixth decade of life) and commonly affecting the lungs (with presentations varying from small bilateral pulmonary nodules to large necrotic and sometimes cavitating lesions), skin, central nervous system, and kidneys, but only very rarely affecting the lymph nodes and spleen. The symptoms associated with LYG depend on the site of disease involvement but mainly include cough, dyspnea or chest pain (in those with pulmonary involvement) and constitutional symptoms such as weight loss and fever. [Orphanet:86869]","descendants":["MONDO:0859749","MONDO:0859747","MONDO:0859748"],"label":"lymphomatoid granulomatosis","mondo":"MONDO:0019466","parents":["MONDO:0017343","MONDO:0018905"],"synonym":{"exact":["LYG"]},"xrefs":{"doid":["DOID:0081307"],"gard":["0006943"],"icd11":["foundation:1890408959"],"icdo":["9766/1"],"meddra":["10025325"],"medgen":["6161"],"mesh":["D008230"],"ncit":["C7930"],"nord":["1385"],"oncotree":["LYG"],"orphanet":["86869"],"sctid":["239940004"],"umls":["C0024307"]}},"umls":{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","icd10am":{"non-preferred":"M9766/1"},"icd10cm":{"non-preferred":"C83.8"},"mesh":{"preferred":"D008230"},"nci":{"non-preferred":["C7930","C40970"],"preferred":"C7930"},"snomed":{"non-preferred":["789177000","41556003","239940004","60337005"],"preferred":["789177000","239940004","60337005"]},"umls":"C0024307"}}