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embryopathy is a teratogenic disorder due to acitretin or etretinate exposure during the first trimester of pregnancy, carrying a risk of fetal malformations of approximately 20%, including central nervous system, craniofacial, ear, thymic, cardiac and limb anomalies. [Orphanet:40366]","label":"acitretin/etretinate embryopathy","mondo":"MONDO:0018442","parents":["MONDO:0016677"],"synonym":{"exact":["fetal acitretin/etretinate syndrome","foetal acitretin/etretinate syndrome","retinoid embryopathy"],"related":["acitretin embryofetopathy","acitretin embryopathy","Acitretine embryofetopathy","fetal acitretin syndrome","foetal acitretin syndrome"]},"xrefs":{"medgen":["1386157"],"mesh":["C538169"],"orphanet":["40366"],"sctid":["725287006"],"umls":["C4510941"]}},"original_id":["orphanet:40366","UMLS:C2931755","UMLS:C4510941"],"umls":[{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","mesh":{"non-preferred":"C538169","preferred":"C538169"},"snomed":{"non-preferred":"890202007","preferred":"890202007"},"umls":"C2931755"},{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","snomed":{"non-preferred":"725287006","preferred":"725287006"},"umls":"C4510941"}]}