{"_id":"MONDO:0005077","_version":1,"ctd":{"chemical_related_to_disease":{"cas_registry_number":"76610-84-9","chemical_name":"cefbuperazone","direct_evidence":"therapeutic","mesh_chemical_id":"C035978","pubmed":"6308296","source":"CTD"},"mesh":"D014917"},"disease_ontology":{"_license":"https://github.com/DiseaseOntology/HumanDiseaseOntology/blob/master/DO_LICENSE.txt","ancestors":["DOID:104","DOID:0050117","DOID:0050339","DOID:4"],"children":["DOID:11750"],"def":"\"A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop).\" [url:http\\://en.wikipedia.org/wiki/Pertussis, url:http\\://www.merck.com/mmhe/sec23/ch272/ch272g.html#sec23-ch272-ch272g-800]","descendants":["DOID:11750"],"doid":"DOID:1116","name":"pertussis","parents":["DOID:0050339"],"synonyms":{"exact":["bordetella infection","WC - Whooping cough","whooping cough"]},"xrefs":{"kegg":"05133","mesh":"D001885","snomedct_us_2025_09_01":"26484003","umls_cui":"C0006015"}},"mondo":{"ancestors":["MONDO:0037872","MONDO:0005113","MONDO:0700096","MONDO:0000001","MONDO:0005550","MONDO:7770010","MONDO:7770006","MONDO:0021678","MONDO:0005087","MONDO:7770008"],"definition":"A contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough. [NCIT:P378]","disease_has_infectious_agent":{"ncbitaxon":["NCBITaxon:520"]},"disease_has_major_feature":{"hp":["HP:0031247"]},"excluded_subClassOf":{"mondo":["MONDO:0000315"]},"label":"pertussis","mondo":"MONDO:0005077","parents":["MONDO:0005087","MONDO:0037872"],"synonym":{"exact":["Bordetella pertussis caused disease or disorder","Bordetella pertussis disease or disorder","Bordetella pertussis infection","Bordetella pertussis infectious disease","pertussis","whooping cough"]},"xrefs":{"doid":["DOID:1116"],"efo":["EFO:0000650"],"gard":["0008692"],"icd9":["033","033.9","033.0"],"meddra":["10047974","10034738"],"medgen":["12159"],"mesh":["D014917"],"ncit":["C85231"],"nord":["1569"],"orphanet":["1489"],"sctid":["27836007"],"umls":["C0043167"]}},"umls":{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","icd10":{"non-preferred":"A37.0"},"icd10am":{"non-preferred":"A37.0"},"icd10cm":{"non-preferred":"A37.0"},"icd9cm":{"non-preferred":"033.0"},"mesh":{"non-preferred":"D014917","preferred":"D014917"},"nci":{"non-preferred":"C85231","preferred":"C85231"},"snomed":{"non-preferred":"27836007","preferred":"27836007"},"umls":"C0043167"}}