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The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.\" [url:http\\://en.wikipedia.org/wiki/Chagas_disease]","descendants":[],"doid":"DOID:12140","name":"Chagas disease","parents":["DOID:10113"],"synonyms":{"exact":["Chagas' disease","chagas' disease with digestive system involvement","chagas' disease with nervous system involvement","chagas' disease with other organ involvement"],"related":["American trypanosomiasis"]},"xrefs":{"gard":"6030","icd10":"B57","kegg":"05142","mesh":"D014355","ncit":"C84629","ordo":"3386","snomedct_us_2025_09_01":"77506005","umls_cui":"C0041234"}},"hpo":{"disease_name":"American 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parasitic infection caused by Trypanosoma cruzi. It is transmitted by insect bites. It is characterized by an acute and chronic phase; in the acute phase patients may have fever, malaise, and swelling at the site of the insect bite. In the chronic phase patients develop hepatosplenomegaly, lymphadenopathy, cardiomyopathy and arrhythmias. [NCIT:C84629]","disease_has_infectious_agent":{"ncbitaxon":["NCBITaxon:5693"]},"label":"Chagas disease","mondo":"MONDO:0001444","parents":["MONDO:0000940","MONDO:0100120"],"synonym":{"exact":["Chagas disease","Chagas' disease","infection by trypanosoma cruzi","Trypanosoma cruzi caused disease or disorder","Trypanosoma cruzi disease or disorder","Trypanosoma cruzi infectious disease"]},"xrefs":{"doid":["DOID:12140"],"gard":["0018795"],"icd10cm":["B57"],"icd10who":["B57"],"icd11":["foundation:1365585570"],"icd9":["086.2"],"meddra":["10001935"],"medgen":["11935"],"mesh":["D014355"],"ncit":["C84629"],"orphanet":["3386"],"sctid":["77506005"],"umls":["C0041234"]}},"original_id":["orphanet:3386","UMLS:C0007932"],"umls":[{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","icd10":{"preferred":"B57"},"icd10am":{"preferred":"B57"},"icd10cm":{"non-preferred":["B57.2","B57"],"preferred":"B57"},"mesh":{"non-preferred":"D014355","preferred":"D014355"},"nci":{"preferred":"C84629"},"snomed":{"non-preferred":"77506005","preferred":"77506005"},"umls":"C0041234"},{"_license":"https://www.nlm.nih.gov/research/umls/knowledge_sources/metathesaurus/release/license_agreement.html","icd9cm":{"non-preferred":"086.2","preferred":"086.2"},"snomed":{"non-preferred":["54570006","186817003","94371000119107"],"preferred":["186817003","94371000119107","54570006"]},"umls":"C0007932"}]}